Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker BEFREE Here, we studied the phenotypic alterations induced by the increased intracellular c-di-AMP levels in <i>Streptococcus gallolyticus</i>, an opportunistic pathogen responsible for septicemia and endocarditis in the elderly.We report that an <i>S. gallolyticus</i> c-di-AMP phosphodiesterase <i>gdpP</i> knockout mutant, which displays a 1.5-fold higher intracellular c-di-AMP levels than the parental strain UCN34, is more sensitive to osmotic stress and is morphologically smaller than the parental strain. 30617242

2019
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 AlteredExpression BEFREE The anti-inflammatory effects of AMP-activated protein kinase (AMPK) activator metformin in sepsis has been revealed. 31002870

2019
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 AlteredExpression BEFREE Cereblon deficiency confers resistance against polymicrobial sepsis by the activation of AMP activated protein kinase and heme-oxygenase-1. 29170136

2018
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker BEFREE Here, we show that AMP-activated protein kinase (AMPK) is a negative regulator of bioenergetic reprogramming in immune cells and suppresses sepsis development in vivo. 29109024

2018
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker BEFREE Stimulation of Brain AMP-Activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in Sepsis. 26252187

2015