Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0039103
Disease: Synovitis
Synovitis
0.030 Biomarker BEFREE The limited improvement in the WOMAC pain score and the lack of synovitis improvement with lutikizumab, together with published results from trials of other IL-1 inhibitors, suggest that IL-1 inhibition is not an effective analgesic/antiinflammatory therapy in most patients with knee OA and associated synovitis. 30653843

2019

Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0039103
Disease: Synovitis
Synovitis
0.030 Biomarker BEFREE The differential regulation of the two forms of IL-1ra mRNAs may play an important role in shoulder pain in rotator cuff diseases, regulating IL-1-induced subacromial synovitis. 11561109

2001

Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0039103
Disease: Synovitis
Synovitis
0.030 AlteredExpression BEFREE The coexpression of both IL-1 and IL-6 by one synovial fibroblast line suggests a mechanism for the perpetuation of synovitis. 1707461

1990