DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Thrombocythemia, Essential ×

Gene: MYB ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4602
Gene Symbol:	MYB

MYB

CUI:	C0040028
Disease:	Thrombocythemia, Essential

Thrombocythemia, Essential

0.220

GeneticVariation

BEFREE

HBS1L-MYB rs9376092 associated only with JAK2 V617F-mutated ET (OR = 1.4; 95% CI = 1.1-1.7; P-value = .003).

29047144

2018

Entrez Id:	4602
Gene Symbol:	MYB

MYB

CUI:	C0040028
Disease:	Thrombocythemia, Essential

Thrombocythemia, Essential

0.220

GeneticVariation

BEFREE

Reduced MYB expression, previously linked to development of an ET-like disease in model systems, associates with rs9376092 in normal myeloid cells.

25849990

2015

Entrez Id:	4602
Gene Symbol:	MYB

MYB

CUI:	C0040028
Disease:	Thrombocythemia, Essential

Thrombocythemia, Essential

0.220

Biomarker

MGD

A recessive screen for genes regulating hematopoietic stem cells.

20610815

2010