Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker BEFREE A high amount of PGE<sub>2</sub> was detected during Mtb infection, and pharmacological inhibition of COX-2 induced a significant reduction of bacterial load and an improved innate immune response in the lungs, independently of baseline LTB<sub>4</sub> levels. 31666208

2020
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker BEFREE COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. 30202030

2018
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 AlteredExpression BEFREE Mycobacterial 3-hydroxyacyl-l-thioester dehydratase Y derived from Mycobacterium tuberculosis induces COX-2 expression in mouse macrophages through MAPK-NF-κB pathway. 24907510

2014