DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Uveomeningoencephalitic Syndrome ×

Gene: ADO ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	84890
Gene Symbol:	ADO

ADO

CUI:	C0042170
Disease:	Uveomeningoencephalitic Syndrome

Uveomeningoencephalitic Syndrome

0.020

Biomarker

BEFREE

In addition, we also successfully replicated the association of VKH syndrome with ADO-ZNF365-EGR2 in a Thai population.

26628628

2016

Entrez Id:	84890
Gene Symbol:	ADO

ADO

CUI:	C0042170
Disease:	Uveomeningoencephalitic Syndrome

Uveomeningoencephalitic Syndrome

0.020

GeneticVariation

BEFREE

We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).

25108386

2014