Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms 		0.030 AlteredExpression BEFREE Elevated serum IL-6 and IL-17 levels in patients with RA induce arthritis and cause mood symptoms, especially depression symptoms. 30848077

2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms 		0.030 Biomarker BEFREE Among all subjects (LLD + control), plasma IL-17A did not correlate significantly with depressive symptoms (rho = -0.009, p = 0.92) but a significant correlation was observed with cognitive assessments (rho = 0.22, p = 0.01). 29069253

2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms 		0.030 AlteredExpression BEFREE In depression, although Th17 cells increase, the lack of a consistent correlation between depression severity and blood IL-17A levels suggests that Th17 cells promote depressive symptoms, which may not be entirely dependent on IL-17. 28779999

2018