Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker BEFREE The F/B ratio was positively related to the detectable IL-1B in TB (R<sup>2</sup>  = 0.97, P < 0.01) and to the IL-4 in LTBI (R<sup>2</sup>  = 0.27, P < 0.05). 30620398

2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker BEFREE The role of IL-1b and inflammasome in the process of LTBI progressing to active TB warrants further investigation. 31781307

2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker BEFREE Within the cohort of HIV-positive subjects, the expression profiles of 7 genes at baseline (FCGR1A, RAB24, TLR1, TLR4, MMP9, NLRC4, and IL1B) could accurately discriminate between active tuberculosis and both latent and no M. tuberculosis infection, largely independently of (in)eligibility for highly active antiretroviral therapy (HAART). 29982697

2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker BEFREE Interleukin-1 beta (IL-1 β) signaling is known to be high in active tuberculosis. 27661435

2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 Biomarker BEFREE Polymorphisms in SIGLEC1 contribute to susceptibility to pulmonary active tuberculosis possibly through the modulation of IL-1ß. 28964857

2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0151332
Disease: Active tuberculosis
Active tuberculosis 		0.060 GeneticVariation BEFREE The high-IL-1β expressing genotype was associated with the development of active tuberculosis, the severity of pulmonary disease and poor treatment outcome in TB patients. 25329476

2014