Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0155094
Disease: Corneal pannus
Corneal pannus 		0.020 Biomarker BEFREE The human tumour necrosis factor (TNF) transgenic (hTNFtg) mouse model of RA was used to analyse the time course of pannus attachment to the cartilage and cartilage destruction, respectively, and crossed hTNFtg mice with interleukin (IL)-1(-/-) animals were used to investigate the role of IL-1 on these TNF-induced mechanisms in vivo. 22258493

2012
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0155094
Disease: Corneal pannus
Corneal pannus 		0.020 AlteredExpression BEFREE However, in some microenvironments such as injured tissue or joint spaces, elevated IL-1 levels may contribute to pathologic processes, for example, proliferation and fibrosis of tissue involved in pannus formation as well as degradation of matrix and abnormal tissue architecture. 3497982

1987