Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0155094
Disease: Corneal pannus
Corneal pannus 		0.040 Biomarker BEFREE Furthermore, the migration of cells from the pannus-like tissue was enhanced by IL-1β, while plica cell migration was enhanced by TNF-α. 24223987

2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0155094
Disease: Corneal pannus
Corneal pannus 		0.040 Biomarker BEFREE The human tumour necrosis factor (TNF) transgenic (hTNFtg) mouse model of RA was used to analyse the time course of pannus attachment to the cartilage and cartilage destruction, respectively, and crossed hTNFtg mice with interleukin (IL)-1(-/-) animals were used to investigate the role of IL-1 on these TNF-induced mechanisms in vivo. 22258493

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0155094
Disease: Corneal pannus
Corneal pannus 		0.040 AlteredExpression BEFREE Pannus-like tissue and the plica express IL-1β and MMP-3. 21371079

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0155094
Disease: Corneal pannus
Corneal pannus 		0.040 AlteredExpression BEFREE However, in some microenvironments such as injured tissue or joint spaces, elevated IL-1 levels may contribute to pathologic processes, for example, proliferation and fibrosis of tissue involved in pannus formation as well as degradation of matrix and abnormal tissue architecture. 3497982

1987