Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 Biomarker BEFREE Both BATFs bind classical AP-1 motifs and interact with in ALCL deregulated AP-1 factors. 29588546

2018

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 AlteredExpression BEFREE In this review, we focus on the impact of deregulated expression of AP-1 TFs in CD30-positive lymphomas including Classical Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma. 29597249

2018

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 Biomarker BEFREE Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. 28659618

2018

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 AlteredExpression BEFREE Deregulated expression of AP-1 transcription factors is implicated in the pathogenesis of various lymphomas such as classical Hodgkin lymphomas, anaplastic large cell lymphomas, diffuse large B cell lymphomas and adult T cell leukemia/lymphoma. 27600282

2017

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 Biomarker BEFREE Here, we discuss the role of AP-1 in the pathogenesis of ALCL and provide an overview of pathological epigenetic changes in ALCL cells. 25961698

2015

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 Biomarker BEFREE The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma. 25145835

2014

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 Biomarker BEFREE Together, our data identify PDGFRB as a previously unknown JUN and JUNB target that could be a highly effective therapy for ALCL. 23064464

2012

Entrez Id: 3726
Gene Symbol: JUNB
JUNB
Ki-1+ Anaplastic Large Cell Lymphoma
0.080 Biomarker BEFREE The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling. 17690253

2007