Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Acute exacerbation of chronic obstructive airways disease
0.020 AlteredExpression BEFREE Significantly higher mRNA levels of NLRP3, Casp-1, ASC, IL-18, IL-1β and higher levels of IL-18 and IL-1β were found in patients with AECOPD than in smokers. 29656319

2018

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Acute exacerbation of chronic obstructive airways disease
0.020 AlteredExpression BEFREE We found that serum IL-1β and IL-17 levels in acute exacerbation of COPD subjects were significantly higher than that in stable COPD or control subjects and were positively correlated to serum C-reactive protein levels, neutrophil % and smoking status (pack-years) but negatively correlated with FEV<sub>1</sub>% predicted in COPD patients. 28490868

2017