Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 GeneticVariation BEFREE A long-range interaction of genetic variants with c-MYC or long non-coding PVT1 at this locus contributes to the genetic risk of prostate cancer. 30808975

2019
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 AlteredExpression BEFREE Consequently, PVT1 exon 9 expression is important for PCa initiation and progression, and holds promise as a therapeutic target in PCa. 31766781

2019
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 GeneticVariation BEFREE Specificities of the former could be explained by genomic events linked with key genes such as DNA damage pathway genes PARP1, CDK12, and the oncogenic long non-coding RNA gene PVT1 at the 8q24 prostate cancer susceptibility locus. 30245085

2019
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 Biomarker BEFREE Our findings suggest that the PVT1/miR-186/Twist1 regulatory axis may be a new therapeutic target for prostate cancer. 29452232

2018
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 AlteredExpression BEFREE Downregulation of lncRNA PVT1 expression inhibits proliferation and migration by regulating p38 expression in prostate cancer. 30250582

2018
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 Biomarker BEFREE Our results suggest that PVT1 played an oncogenic role in prostate cancer and could be used as a potential biomarker for diagnosis of prostate cancer. 29050519

2017
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 AlteredExpression BEFREE Our results showed that miR-146a was downregulated and negatively correlated with PVT1 level in prostate cancer. 27794184

2016
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 GeneticVariation BEFREE MicroRNA-1207-3p is encoded at the non-protein coding gene locus PVT1 on the 8q24 human chromosomal region, an established PCa susceptibility locus. 27693493

2016
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 Biomarker BEFREE Our aim was to determine if any PVT1 transcripts play a role in aggressiveness and racial disparity in PCa. 26703666

2015
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.100 GeneticVariation BEFREE A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression. 21814516

2011