Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 Biomarker BEFREE Our results suggest that SLC22A18 may act as a tumor suppressor by regulating the expression levels of cell growth-related proteins, and vinca alkaloids might show therapeutic efficacy against low-SLC22A18-expressing breast cancer. 30145211

2018

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 AlteredExpression BEFREE The results of Kaplan-Meier analysis indicated that SLC22A18 expression was associated with relapse-free survival (RFS) of breast cancer. 21144813

2011

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 Biomarker BEFREE Gain of imprinting of SLC22A18 sense and antisense transcripts in human breast cancer. 16624517

2006

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 AlteredExpression BEFREE HET/SAF-B protein and mRNA were detected at varying levels in all of the eight breast cancer cell lines examined. 10999774

2000

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 GeneticVariation BEFREE Because this region frequently is altered in neoplasms and in the genetic disease Beckwith-Wiedemann syndrome, we carried out a mutational analysis in tumor cell lines and Beckwith-Wiedemann syndrome samples that resulted in the identification of genetic alterations in the BWR1A gene: an insertion that introduced a stop codon in the breast cancer cell line BT549 and a point mutation in the rhabdomyosarcoma cell line TE125-T. 9520460

1998

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 Biomarker BEFREE We were able to show that HET is localized in the nuclear matrix in various breast cancer cell lines. 9328833

1997

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 Biomarker CTD_human

Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.460 Biomarker HPO