Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 Biomarker BEFREE Voluntary wheel running activates Akt/AMPK/eNOS signaling cascades without improving profound endothelial dysfunction in mice deficient in α-galactosidase A. 31120949

2019
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 GeneticVariation BEFREE Fabry disease is secondary to deficiency of the lysosomal enzyme alpha-galactosidase A, leading to altered glycosphingolipid metabolism and accumulation that is often associated with endothelial dysfunction. 16720469

2006
Entrez Id: 2717
Gene Symbol: GLA
GLA
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 GeneticVariation BEFREE In Fabry's disease, the characteristic mutation in the alpha-galactosidase A (alpha-gal A) gene induces large deposits of glycosphingolipids, particularly concentrated in ECs, a process associated with endothelial dysfunction. 12121349

2002