Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.040 GeneticVariation BEFREE Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with coexistent hypertrophic cardiomyopathy and coronary spastic angina. 15778808

2005
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.040 GeneticVariation BEFREE We recently reported that a mutation (-786T-->C) in the promoter region of the endothelial nitric oxide synthase (eNOS) gene reduced transcription of the gene and was strongly associated with coronary spastic angina and myocardial infarction. 11063722

2000
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.040 GeneticVariation BEFREE We also revealed that the T-786-->C variant is strongly associated with coronary spastic angina and leads to the reduction of the eNOS gene promoter activity. 11131266

2000
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.040 GeneticVariation BEFREE We have identified a missense variant, Glu298Asp, in exon 7 of the eNOS gene and demonstrated that it is associated with both coronary spastic angina and myocardial infarction. 9674630

1998
Entrez Id: 5333
Gene Symbol: PLCD1
PLCD1
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.010 AlteredExpression BEFREE Increased PLC-δ1 activity enhances coronary vasomotility such as that seen in patients with coronary spastic angina. 22265909

2012
Entrez Id: 64333
Gene Symbol: ARHGAP9
ARHGAP9
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.010 GeneticVariation BEFREE Mutation of ARHGAP9 in patients with coronary spastic angina. 19911011

2010
Entrez Id: 6444
Gene Symbol: SGCD
SGCD
CUI: C0948698
Disease: Coronary spastic angina
Coronary spastic angina 		0.010 GeneticVariation BEFREE Impact of delta-sarcoglycan gene polymorphism on the occurrence of coronary spastic angina in Japanese patients with hypertrophic cardiomyopathy. 17652892

2007