Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 Biomarker BEFREE Our previous studies showed that Fibroblast growth factor receptor 3 (FGFR3) contributed to cell growth in lung cancer. 29850625

2018

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 Biomarker BEFREE Overall, this study provides new insights into the PRMT5/miR-99 family/FGFR3 axis in regulating lung cancer progression and identifies PRMT5 as a promising prognostic biomarker and therapeutic target. 29679612

2018

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE We identified 4 patients with bladder cancer and 2 patients with lung cancer harboring the FGFR3-BAIAP2L1 fusion through PCR and FISH assay screens. 25589496

2015

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 GeneticVariation BEFREE A novel somatic FGFR3 mutation in primary lung cancer. 24452392

2014

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 Biomarker BEFREE Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing. 23661334

2013

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 AlteredExpression BEFREE Furthermore, miR-99a downregulation is associated with mTOR/FGFR3 upregulation in various human lung cancer cells/tissues. 21383697

2011

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.070 Biomarker BEFREE Use of an FGFR3 inhibitor (PD173074) obtained similar results with suppression of the autophosphorylation extracellular signal-regulated kinase pathway in HSC-2 cells and lung cancer cell lines. 21577207

2011