Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 Biomarker BEFREE These results suggest a contribution of TMEM70 downregulation to the Warburg effect, which directs tumor promotion and progression in GST-P+-linked hepatocarcinogenesis in rats. 28903497

2017

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 Biomarker BEFREE All gene products of the 4 selected genes showed decreased immunoreactivity forming negative liver cell foci in a subpopulation of glutathione S-transferase placental form (GST-P)<sup>+</sup> foci in TAA-promoted rat livers in a two-stage hepatocarcinogenesis model. 27914986

2017

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 Biomarker BEFREE Based on the close relationship between GST-P and neoplastic hepatocytes, these data allowed us to hypothesize that cell proliferation following signal transduction other than the mitogen-activated protein kinase (MAPK)/ERK pathway may play a crucial role in early-stage furan-induced hepatocarcinogenesis. 27143483

2017

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 Biomarker BEFREE Limited epidemiological evidence suggests that genetic polymorphisms of drug-metabolizing enzymes such as cytochrome P450 (CYP), glutathione S-transferase (GST) and N-acetyltransferase (NAT) may be involved in tobacco-related hepatocarcinogenesis. 19643819

2009

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 AlteredExpression BEFREE In particular, C/EBPalpha was required for the suppression of GST-P gene in normal liver, whereas the Nrf2/MafK heterodimer was required for the activation of this gene during hepatocarcinogenesis. 17434454

2007

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 GeneticVariation BEFREE This study was conducted to investigate the modifying effect of glutathione S-transferase (GST) M1 and T1 polymorphisms on aflatoxin-induced hepatocarcinogenesis among chronic hepatitis B virus surface antigen (HBsAg) carriers. 11470760

2001

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.070 GeneticVariation BEFREE This study was carried out to elucidate the effect of glutathione S-transferase (GST) Ml and Tl polymorphisms on the aflatoxin-related hepatocarcinogenesis among chronic carriers of hepatitis B surface antigen (HBsAg). 8659516

1996