Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 AlteredExpression BEFREE In the rat hepatocarcinogenesis model, unexpectedly, CYP2E1 activity was found to decrease from hepatofibrosis to hepatocarcinogenesis. 29917271

2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE As CYP2E1 is linked to the formation of carcinogenic etheno DNA adducts in ALD patients, a causal role of alcohol-induced CYP2E1 in hepatocarcinogenesis is implicated. 29120493

2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 AlteredExpression BEFREE The results showed that the CYP2E1 constitutive activity was strongly correlated with tumor incidence and severity of liver tumorigenesis (nodule numbers and size), whereas inhibition of CYP2E1 activity decreased hepatocyte proliferation, liver injury, and liver carcinogenesis in the presence of DEN. 29467309

2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 GeneticVariation BEFREE To evaluate CYP2E1 polymorphisms in liver carcinogenesis through meta-analysis. 27637154

2017
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE The elucidation of a HBx-HNF4α-CYP2E1 pathway provides novel insight into the molecular mechanism underlining chronic HBV infection associated hepatocarcinogenesis. 25238230

2014
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 AlteredExpression BEFREE Differential expression of CYP2E1 may play a pleiotropic role in the multistep process of liver carcinogenesis. 20404016

2010
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 GeneticVariation BEFREE Polymorphisms of CYP2E1 may play an important role in cigarette smoking-related hepatocarcinogenesis. 7557094

1995