Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 AlteredExpression BEFREE Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. 24398550

2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE This allows concluding that COX-2 is insufficient for modifying the hepatocarcinogenesis course mediated by c-myc/TGF-α. 23579063

2013
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 AlteredExpression BEFREE Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. 22242948

2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE Although COX-2 is known to mediate the growth and progression of several human cancers including hepatocellular carcinoma (HCC), the role of mPGES-1 in hepatocarcinogenesis is not well established. 21743491

2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE The contribution of COX-2-dependent PGs to the development of DEN-induced hepatocarcinogenesis was evaluated in Tg mice, Tg hepatocyte-like cells, and nude mice and the analysis revealed that COX-2 expression favors the development of preneoplastic foci without affecting malignant transformation. 21356386

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE COX-2 might represent an important cellular effector of HBx that contributes to hepatitis B virus-associated hepatocarcinogenesis. 15218507

2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.070 Biomarker BEFREE Cyclooxygenase 2 (COX-2) has been suggested to be associated with liver carcinogenesis. 12115513

2002