Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE The nanocarrier was also able to inhibit the replication in human hepatoma cells supporting a subgenomic HCV replicon (Huh-7 NS3-3'). 27451369

2017

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Depletion of TM6SF2 disturbs membrane lipid composition and dynamics in HuH7 hepatoma cells. 28434889

2017

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE In this study, we investigated the mechanisms underlying PV-mediated inhibition of 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced cell invasion and inhibition of secreted and cytosolic MMP-9 production in human hepatoma cells (Huh-7 and HA22T). 27222069

2017

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Lipid-loaded Huh7 human hepatoma cells had a 38% reduction in CYP3A4 activity and 80% lower CYP3A4 mRNA expression compared with the control. 26231377

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE In vivo efficacy of human recombinant factor IX produced by the human hepatoma cell line HuH-7. 25981983

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE To understand this feature, we previously performed genetic analysis of HCV in the long-term culture of human hepatoma HuH-7-derived HCV RNA-replicating cell lines. 24625789

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression BEFREE HRG overexpression in Huh7 and MHCC-97H hepatoma cell lines led to decreased cell proliferation, colony-forming ability, and tumor growth, and increased cell apoptosis. 26336134

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Furthermore, CYP3A4 activity in DMSO-treated HuH-7 cells was compared to that in a human hepatoma cell line (HepG2/C3A) and human bipotent progenitor cell line (HepaRG), which yielded the following ranking: HepaRG > DMSO-treated HuH-7 > HepG2/C3A cells. 26377104

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression BEFREE Furthermore, Huh7 and HT1080 cancer cells treated with oAd/shMet-ABP-PEG-HCBP1 complex had significantly decreased Met and VEGF expression in hepatoma cancer, but not in non-hepatoma cancer. 26437261

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Different steps of HCV life cycle were assessed in HCV-infected human Huh-7 hepatoma cells overexpressing ADRP upon transduction with a lentiviral vector. 26731658

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Results were validated using primary human hepatocytes (PHHs) and mechanistic analyses were conducted in engineered Huh7 hepatoma cells with reconstituted innate signaling pathways. 25908268

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Infection studies were performed in the hepatoma cell line HuH7/Scr and in primary human hepatocytes. 26070407

2016

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression BEFREE Exosomes prepared from SILAC-labeled hepatoma cell line Huh-7 transfected with HBx, wildtype, or HBx-null HBV replicon plasmids were analyzed by LC-MS/MS. 25265333

2015

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE This study found that 4AAQB inhibited HepG2 and HuH-7 hepatoma cell growth in both in vitro and in vivo models and exhibited pronounced inhibitory effects on HuH-7 tumor growth in xenograft and orthotopic models. 25494404

2015

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression BEFREE Using a CDC37-specific small oligo-siRNA, we silenced CDC37 expression in HepG2 and Huh7 hepatoma cell lines, and observed inhibition of in vitro cell proliferation, cell cycle arrest at the G1 phase, and enhanced apoptosis. 25098386

2015

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression BEFREE The fact that Huh-7 and HepG2 cell lines provided similar results lent weight to the relationship of AChE expression with cell cycle progression in hepatoma cell lines at least. 25869328

2015

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Global epigenetic reactivation correlated with C1-INH mRNA synthesis and protein secretion in Huh7 hepatoma cells. 25053016

2015

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE In vitro IFN-λ1 treatment of Hep3B and Huh7 human hepatoma cell lines increased MHC class I expression, activated JAK-STAT signaling pathways, induced IFN-stimulated gene expression, and inhibited hepatitis B surface antigen (HBsAg) expression. 24769671

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE HBSP could enhance the cell proliferation, accelerate the G1/S transition, and promote cell transformation and tumorigenesis of B[alpha]P-treated Huh-7 hepatoma cells. 24758376

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Coimmunoprecipitation experiments in Huh7 hepatoma cells confirmed the interaction of TIP47 with full-length NS5A. shRNA-mediated knockdown of TIP47 caused a more than 10-fold decrease in the propagation of full-length infectious HCV in Huh7.5 hepatoma cells. 23593007

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 AlteredExpression BEFREE We studied the effects of different immunosuppressants, including steroids, calcineurin inhibitors (tacrolimus [FK506] and cyclosporin A), and mycophenolic acid (MPA, an inhibitor of inosine monophosphate dehydrogenase) on HEV replication in human hepatoma cell line Huh7. 24582714

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE HuH7 human hepatoma cells expressing both TLR3 and RIG-I produced maximal CXCL10 during early HCV infection. 23770038

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 GeneticVariation BEFREE In vitro cytotoxicity and in vivo therapeutic studies were conducted in the human cancer cell lines A-375 (melanoma), HuH-7 and Hep-G2 (hepatoma), Capan-1 (pancreatic), NCI-N87 (gastric), and Raji Burkitt lymphoma. 23427296

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells. 24763554

2014

Entrez Id: 284424
Gene Symbol: MIR7-3HG
MIR7-3HG
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.100 Biomarker BEFREE These results demonstrate a causal role for JNK and caspases in TNF+CHX-induced apoptosis of Huh7 human hepatoma cells. 23751896

2014