Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 AlteredExpression BEFREE MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer. 30694565

2019

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 Biomarker BEFREE Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer. 29440171

2018

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 Biomarker BEFREE Human Papillomavirus Regulates HER3 Expression in Head and Neck Cancer: Implications for Targeted HER3 Therapy in HPV<sup>+</sup> Patients. 27986750

2017

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 AlteredExpression BEFREE Although heregulin and human epidermal growth factor receptor 3 (HER3) are frequently expressed at high levels in patients with head and neck cancer, their prognostic value remains unclear. 26195293

2015

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 Biomarker BEFREE Human epidermal growth factor receptor 3 (HER3) blockade with U3-1287/AMG888 enhances the efficacy of radiation therapy in lung and head and neck carcinoma. 23998444

2013

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 AlteredExpression BEFREE erbB-3, a third member of the erbB/epidermal growth factor receptor gene family: its expression in head and neck cancer cell lines. 8286103

1993

Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma
0.360 CausalMutation CGI