Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.350 GeneticVariation BEFREE EZH2 mutations correlate with aberrant erythropoiesis in PMF patients, exemplified by impaired maturation and cell cycle arrest of erythroid progenitors. 29907810

2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.350 GeneticVariation BEFREE Elevated expression of the EZH2 gene in CALR-mutated patients with primary myelofibrosis. 29560522

2018
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.350 Biomarker BEFREE Bone marrow fibrosis and mutations in ASXL1, SRSF2, EZH2, and IDH1/2 have been found to be additional prognostic factors in primary myelofibrosis (PMF). 28948488

2017
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.350 GeneticVariation BEFREE Additionally, chromatin modification genes (ASXL1 and EZH2) were frequently mutated in PMF patients (0·50) and, to a significantly lesser extent, in ET (0·13) and PV (0·07). 27447873

2016
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.350 GeneticVariation BEFREE We conclude that EZH2 mutations are independently associated with shorter survival in patients with PMF. 21921040

2011