Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.450 AlteredExpression BEFREE High FGFR1 expression was associated with age, malignancy, tumor location and tumor grade among astrocytomas. 30931252

2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.450 GeneticVariation BEFREE Pediatric LGG show alterations in FGFR1 and BRAF in pilocytic astrocytomas and FGFR1 alterations in diffuse astrocytomas, each converging on the mitogen-activated protein kinase signaling pathway. 25664944

2015
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.450 AlteredExpression BEFREE Transplantation of Trp53-null neonatal astrocytes expressing FGFR1 with the duplication involving the TKD into the brains of nude mice generated high-grade astrocytomas with short latency and 100% penetrance. 23583981

2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.450 AlteredExpression BEFREE Glioblastoma (the most malignant form of astrocytoma) cell lines, which exhibit the same pattern of FGFR gene expression as glioblastoma biopsies, were used to evaluate the contribution of FGFR1 expression to glioblastoma cell growth. 10498824

1999
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.450 Biomarker BEFREE Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas. 7964981

1994