Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.430 Biomarker BEFREE Therefore, herbs-partitioned moxibustion combined with acupuncture can prevent intestinal epithelial mesenchymal transition by inhibiting abnormal expression of TGF<i>β</i>1, T<i>β</i>R2, Smad3, and Snail in the TGF-<i>β</i>1-Smad-Snail pathway in Crohn's disease. 31275422

2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.430 AlteredExpression BEFREE The high SMAD7 immunoreactivity and lack of p-SMAD3 expression in the LP suggests defective TGF-β signaling in the LP in EE similar to a previously reported SMAD7-mediated inflammatory pathway in refractory CD and Crohn's disease. 29415065

2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.430 GeneticVariation BEFREE SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease. 24461721

2014