Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
CUI: C0013146
Disease: Drug abuse
Drug abuse 		0.340 GeneticVariation BEFREE We investigate the mechanism of time-dependent inhibition (TDI) of human cytochrome P450 2D6 (CYP2D6) by 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), one of the most widespread recreational drugs of abuse. 30114388

2018
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
CUI: C0013146
Disease: Drug abuse
Drug abuse 		0.340 Biomarker BEFREE Cytochrome P450 2D6 (CYP2D6) is a member of the cytochrome P450 (CYP) superfamily involved in the biotransformation of drugs and substances of abuse encountered in clinical toxicology. 25998998

2015
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
CUI: C0013146
Disease: Drug abuse
Drug abuse 		0.340 Biomarker BEFREE Inhibition of cytochrome P450 2D6 modifies codeine abuse liability. 10917405

2000
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
CUI: C0013146
Disease: Drug abuse
Drug abuse 		0.340 Biomarker BEFREE In human experimental studies, we have shown that CYP phenotype and genotype affect abuse liability of CYP2D6 metabolized drugs of abuse. 10911933

2000