Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.350 AlteredExpression BEFREE We have previously shown that HSC niche proteins stromal cell-derived factor-1α (SDF-1α), C-X-C chemokine receptor type 4 (CXCR4), osteopontin (OPN), and cathepsin K (CatK) are expressed in hypoxic GSC niches around arterioles in five human glioblastoma samples. 29297738

2018
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.350 AlteredExpression BEFREE Cathepsin K and X proteins were abundantly and heterogeneously expressed in glioblastoma tissue. 30367810

2018
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.350 Biomarker BEFREE On the basis of these findings, it is concluded that cathepsins B, X and K have distinct functions in GBM and that cathepsin K is the most likely GSC niche-related cathepsin of the three cathepsins investigated. 30046941

2018
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.350 Biomarker BEFREE Confocal imaging of human GBM tissue sections confirmed co-localization of SDF-1α and CatK in GSLC niches. 28040478

2017
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.350 AlteredExpression BEFREE Expression analysis of all protease genes reveals cathepsin K to be overexpressed in glioblastoma. 25356585

2014