Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 AlteredExpression BEFREE Estrogen receptor variant ER-α36 promotes tamoxifen agonist activity in glioblastoma cells. 30417588

2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 Biomarker BEFREE ER-α36, a novel variant of ERα, is involved in the regulation of Tamoxifen-sensitivity of glioblastoma cells. 26898538

2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 Biomarker BEFREE We present data that letrozole, an extensively used aromatase inhibitor in the treatment of estrogen receptor-positive breast tumors in postmenopausal women, may be potentially used in the treatment of glioblastomas. 25695958

2015
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 AlteredExpression BEFREE These data suggest that PR-B is the predominant isoform expressed in human astrocytomas grades III and IV, and that estrogen receptor-alpha is not expressed in astrocytomas grade IV. 11604247

2001