Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 30817
Gene Symbol: ADGRE2
ADGRE2
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker BEFREE Given its proven roles in tumor invasion, expression among aggressive genetic subtypes of GBM, and association with overall survival, CD97 is an attractive therapeutic target for patients with GBM. 25714433

2015
Entrez Id: 30817
Gene Symbol: ADGRE2
ADGRE2
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker BEFREE Wilms tumor 1 gene, CD97, and the emerging biogenetic profile of glioblastoma. 25434383

2014
Entrez Id: 30817
Gene Symbol: ADGRE2
ADGRE2
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker BEFREE CD97 promotes invasion and migration in GBM, but has no effect on tumor proliferation. 23658650

2013
Entrez Id: 30817
Gene Symbol: ADGRE2
ADGRE2
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression BEFREE Of these, CD97 expression was consistently suppressed across the 3 different GBM cell lines studied and was found on further investigation to significantly impact GBM cell invasiveness. 22313360

2012
Entrez Id: 30817
Gene Symbol: ADGRE2
ADGRE2
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker BEFREE When comparing cells transfected with siRNA targeting EMR2 to those transfected with a negative, scramble control, there was no difference in proliferation over 72 h in the SF767 and G55 glioblastoma cell lines. 21503828

2011