Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5478
Gene Symbol: PPIA
PPIA
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression BEFREE After systemic administration of these new siRNA delivery NPs, they can target the glioma cells and efficiently inhibit the GBM tumor growth by silencing the expression of cyclophilin A (CypA), which is up-regulated in brain cancer and plays an important role in malignant transformation of brain cancer and maintaining glioma cell stemness. 30386245

2018
Entrez Id: 5478
Gene Symbol: PPIA
PPIA
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 Biomarker BEFREE These results not only establish the relevance of CypA to glioblastoma growth in vitro and in vivo, but also suggest that small interfering RNA-based CypA knockdown could be an effective therapeutic approach against glioblastomas. 20454998

2011