Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 80727
Gene Symbol: TTYH3
TTYH3
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.010 GeneticVariation BEFREE We used whole-exome and RNA sequencing in a patient with glioblastoma multiforme to identify a rearrangement between TTYH3, encoding a membrane-resident, calcium-activated chloride channel, and BRAF intron 1, resulting in a TTYH3-BRAF fusion protein that retained all features essential for BRAF autoinhibition. 31558800

2020