Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.340 AlteredExpression BEFREE The correlation between matrix stiffness as a mechanical property, TAZ as a potential mechanotransducer, and OPN as a matricellular factor suggests possible effects of mechanical features of the ECM on the expression of the aforementioned profibrogenic markers, which is predominant in autoimmune- and alcohol-related cirrhosis. 31696937

2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.340 Biomarker BEFREE Evaluation of Osteopontin as a Biomarker in Hepatocellular Carcinomas in Egyptian Patients with Chronic HCV Cirrhosis 29693976

2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.340 GeneticVariation BEFREE Area under receiver operating characteristics curves in distinguishing HCC from chronic liver disease (CLD; CH and LC) were 0.782 (95% CI; 0.729-0.834) for OPN and 0.888 (95% CI; 0.850-0.927) for AFP. 26514514

2015
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.340 Biomarker BEFREE OPN pathway was evaluated in livers from patients with progressive stages of human ALD and serum from drinkers with and without liver cirrhosis. 25278703

2014