Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 AlteredExpression BEFREE Direct effects on insulin and AMP-activated protein kinase (AMPK) signaling were studied in human hepatoma HepG2 cells. 30926950

2019
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 AlteredExpression BEFREE We previously found that berberine could decrease the intracellular triglyceride content in human hepatoma HepG2 cells through activation of AMP-activated protein kinase (AMPK), a major regulator of lipid metabolism. 30268048

2018
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 AlteredExpression BEFREE We presently investigated aspirin's promotion of AMP-activated protein kinase (AMPK) pathway activation in human hepatoma HepG2 cells by examining AMPK expression, the promotion of AMPK activation. 25743752

2015
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.240 Biomarker BEFREE These results showed a cross-talk between cyclic-AMP and JAK/STAT pathways in liver tumors and they reinforce the role of STAT3 activation in liver tumorigenesis. 21835143

2012