Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.340 Biomarker BEFREE Neutrophils from patients with COPD showed enhanced chemotactic responses toward both CXCL1 and leukotriene B<sub>4</sub> compared with control cells. 30395484

2019
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.340 AlteredExpression BEFREE Sputum CXCL1 levels in COPD and ACO patients were higher than in IP patients, whereas sputum CXCL8 levels were not. 30676127

2018
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.340 Biomarker BEFREE Within this context, we now show increased expression of the C-X-C chemokines (CXCL1 and CXCL2) and their receptor CXCR2, and the intercellular cellular adhesion molecule-1 (ICAM-1), in the lung tissues of patients with COPD. 26747783

2016
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.340 Biomarker BEFREE The analysis of gene expressions using a qPCR array revealed that many cytokines contributing to the pathogenesis and systemic inflammation in chronic obstructive pulmonary disease (COPD), including CCL2, CCL20, CSF2, CXCL1, CXCL10, IL1B and TNFα, were down-regulated by MA130 but not by a PKCζ-inactive control compound. 27516147

2016