Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker BEFREE This study demonstrates a novel regulatory function of Nur77 with linkage of the FAO-NADPH-ROS pathway during metabolic stress, suggesting Nur77 as a potential therapeutic target in melanoma. 29395065

2018
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker BEFREE It has been shown to have an inhibitory effect on NADPH oxidase, an enzyme family which is found in abundance in reactive oxygen-driven tumors such as melanoma and lymphoma. 28833549

2018
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker BEFREE Using the highly metastatic human melanoma cell line MV3, we observed that pharmacological NADPH oxidase inhibition reduced melanoma viability and induced dramatic cellular shape changes. 24911159

2014