Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.150 GeneticVariation BEFREE CONCLUSIONS PTPN22 rs2488457 and rs1217414 polymorphisms may be risk factors for AS occurrence. 28555069

2017
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.150 GeneticVariation BEFREE Association of PTPN22 polymorphsims and ankylosing spondylitis susceptibility. 25755798

2015
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.150 GeneticVariation BEFREE Our findings indicated that PTPN22 -1123G/C and CTLA-4 +49A/G genetic polymorphisms have a combined effect on the development of AS. 24212676

2014
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.150 GeneticVariation BEFREE The study showed that a functional variant of PTPN22 confers risk for VKH syndrome but not for AAU+AS+ in a Chinese Han population, which may be due to a modulation of the PTPN22 expression, PBMC proliferation and IL-10 production. 24816862

2014
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.150 Biomarker BEFREE The PTPN22 gene might be associated with AS in a central south Chinese Han population. 24749936

2014