Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0039483
Disease: Giant Cell Arteritis
Giant Cell Arteritis 		0.340 GeneticVariation BEFREE Although other vasculitides, such as giant cell arteritis (GCA) or immunoglobulin A vasculitis, have not benefitted by the great advantage of the large-scale genetic analyses yet, some interesting associations have been recently suggested, such as the classical functional PTPN22 allele rs2476601 (rs2476601" genes_norm="26191">R620W) with GCA. 25405820

2015
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0039483
Disease: Giant Cell Arteritis
Giant Cell Arteritis 		0.340 GeneticVariation BEFREE In the non-HLA region, we confirmed a key role for the functional PTPN22 rs2476601 variant and proposed other putative risk loci for GCA involved in Th1, Th17, and Treg cell function. 25817017

2015
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0039483
Disease: Giant Cell Arteritis
Giant Cell Arteritis 		0.340 GeneticVariation BEFREE Our results suggest that the PTPN22 polymorphism rs2476601/rs2476601" genes_norm="26191">R620W plays an important role in the genetic risk to GCA. 23946333

2013
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0039483
Disease: Giant Cell Arteritis
Giant Cell Arteritis 		0.340 GeneticVariation BEFREE Our results do not support potential involvement of PTPN22 gene polymorphism in the susceptibility or clinical expression of GCA. 16078327

2005