Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.360 Biomarker BEFREE Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance. 30936462

2019
Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.360 AlteredExpression BEFREE Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. 29496493

2018
Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.360 AlteredExpression BEFREE The Axl receptor tyrosine kinase has been demonstrated to be elevated and activated in many human cancers including liver, lung, breast, and pancreatic cancer. 27629742

2016
Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.360 Biomarker BEFREE We conclude that Gas6-induced Axl signaling is a critical driver of pancreatic cancer progression and its inhibition with low-dose warfarin or other Axl-targeting agents may improve outcome in patients with Axl-expressing tumors. 26206560

2015
Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.360 Biomarker BEFREE Our in vitro and preclinical in vivo data demonstrate that anti-human AXL mAbs could represent a new approach to the pancreatic cancer immunotherapy. 24240689

2014
Entrez Id: 558
Gene Symbol: AXL
AXL
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas 		0.360 AlteredExpression BEFREE The immunohistochemical expression of Axl protein was assessed in a panel of 99 archival pancreatic cancers. 19252414

2009