×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
AlteredExpression
BEFREE
Low expression of SPARC in gastric cancer -associated fibroblasts leads to stemness transformation and 5-fluorouracil resistance in gastric cancer .
31139014
2019
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
Biomarker
BEFREE
Furthermore, FN1, TIMP1, MMP2, and SPARC are correlated with SERPINE1 and may serve as therapeutic targets in reversing EMT in GC .
31218131
2019
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
AlteredExpression
BEFREE
Immunohistochemical analysis of SPARC expression was performed in 117 surgically resected GC specimens, and the localization of SPARC positive cells, as well as the rassociation between SPARC expression and clinicopathological characteristics were evaluated.
29403557
2018
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
GeneticVariation
BEFREE
SPP1 rs4754 and its epistatic interactions with SPARC polymorphisms in gastric cancer susceptibility.
28962925
2018
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
Biomarker
BEFREE
The investigations of SERPINE1 and SPARC may promote their predictive and prognostic value in GC .
30410354
2018
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
AlteredExpression
BEFREE
Western blotting and immunofluorescence staining were applied for verifying the endogenous expression of SPARC in human cell lines of gastric cancer and fibroblast.
29156791
2017
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
Biomarker
BEFREE
SPARC suppressed the invasion and migration of GC by reducing MMP-7, MMP-9, N-cadherin, Sp1 and p-ERK1/2 expression.
24676680
2014
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
Biomarker
BEFREE
Overexpression of the SPARC gene may be a useful independent predictor of outcomes in patients with gastric cancer .
24018911
2013
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
GeneticVariation
BEFREE
An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence.
22491017
2013
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
Biomarker
BEFREE
Thus, targeting of SPARC could be an effective therapeutic approach against gastric cancer .
20525171
2010
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
Biomarker
BEFREE
These data indicate the potential of SPARC as a prognostic marker for gastric cancer .
15558074
2004
×
Entrez Id:
6678
Gene Symbol:
SPARC
SPARC
Stomach Carcinoma
0.300
AlteredExpression
BEFREE
The present results suggest that osteonectin is highly expressed in reactive stroma associated with invasive differentiated adenocarcinomas and that it may serve as a useful clinical diagnostic marker for stomach cancer .
12104055
2002