Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.060 Biomarker BEFREE In this study, we mainly investigated the function of miR-139-3p in the progression of ovarian cancer. 31806990

2019
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.060 AlteredExpression BEFREE We aimed to investigate the expression and function of miR-139 in OC. 31839712

2019
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.060 AlteredExpression BEFREE In addition, ROCK2 expression was upregulated and was inversely correlated with miR-139-5p levels in OC tissues. 28653604

2018
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.060 AlteredExpression BEFREE In addition, MAPK activation and RNF2 were related to cisplatin resistance of OC. miR-139-5p was downregulated in cisplatin-resistant OC tissues, and miR-139-5p overexpression could inhibit cell vitality, reduce cisplatin resistance, and promote apoptosis of OC cells. 29719173

2018
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.060 AlteredExpression BEFREE Recovery of miR-139-5p suppressed the expression of c-Jun and thus reversed cisplatin-resistance in ovarian cancer. 30439707

2018
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.060 Biomarker BEFREE MiR-139/ATP7A/B axis can be a reliable biomarker for ovarian cancer diagnosis, and may affect the chemoresistance of ovarian cancer to cisplatin-based chemotherapy; rescuing miR-139 expression thus to inhibit ATP7A/B might contribute to dealing with the chemoresistance of ovarian cancer. 29594361

2018