Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 Biomarker BEFREE Mutations in the H7 HA and PB1 genes of avian influenza a viruses increase viral pathogenicity and contact transmission in guinea pigs. 31503518

2019
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 AlteredExpression BEFREE Our results from this study indicate that influenza A virus upregulates cellular PRPF8 gene expression through viral NS1 and PB1 proteins to increase virus production. 28110426

2017
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 AlteredExpression BEFREE Together, these data reveal a novel strategy exploited by influenza A virus to fine-tune virus replication dynamics and host antiviral response through regulating PB1 protein expression. 25519170

2015
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 AlteredExpression BEFREE Influenza A viruses (IAVs) express the PB1-F2 protein from an alternate reading frame within the PB1 gene segment. 25787281

2015
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 Biomarker BEFREE Selection of PB1 gene segment in the pandemics, variable size and pleiotropic effect of PB1F2 intrigued us to analyze amino acid sequences of this protein in various influenza A viruses. 22788742

2013
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 Biomarker BEFREE Translation of influenza A virus PB1-F2 occurs in a second open reading frame (ORF) of the PB1 gene segment. 23885074

2013
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 Biomarker BEFREE A DNA vaccine expressing PB1 protein of influenza A virus protects mice against virus infection. 22294447

2012
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 Biomarker BEFREE The results showed that miRNA 323 (miR-323), miR-491, and miR-654 inhibit replication of the H1N1 influenza A virus through binding to the PB1 gene. 20554777

2010
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
CUI: C2062441
Disease: Influenza A
Influenza A 		0.090 Biomarker BEFREE Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics. 2795713

1989