Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.240 GeneticVariation BEFREE EDN1 rs4714384 is very likely an important biomarker of CV events in ESRD patients. 28882114

2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.240 GeneticVariation BEFREE Recent studies have reported that EDN1 and EDNRA polymorphisms can influence the age of onset of end-stage renal disease in ADPKD. 21894000

2011
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.240 GeneticVariation BEFREE We examined the influence of three single-nucleotide polymorphisms of the ET-1 gene (EDN1)--K198N, 3A/4A, and T-1370G--on the progression of ADPKD towards end-stage renal disease (ESRD). 16943682

2006
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.240 GeneticVariation BEFREE We evaluated the role of the neuronal constitutive (NOS1) and endothelial constitutive (NOS3) nitric oxide synthase genes and the endothelin-1 (EDN-1) gene in predisposition to chronic renal failure in African-Americans. 11071967

2000