Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10252
Gene Symbol: SPRY1
SPRY1
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.010 Biomarker BEFREE Our findings demonstrate that loss of Spry1 attenuates mitogen-induced VSMC proliferation, and thus injury-induced neointimal hyperplasia likely via insufficient activation of Akt signaling causing decreased cyclinD1 and increased p27<sup>Kip1</sup> and a subsequent decrease in Rb and cdc2 phosphorylation. 29105817

2018