Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 GeneticVariation BEFREE FHL2 modulates proliferation and migration via mitogen-activated protein kinase (MAPK) and PI3K-AKT signalling, leading to arterial wall thickening and thus neointimal hyperplasia. 31714683

2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 Biomarker BEFREE Collectively, the data allow us to conclude that high level CKLF1 after artery injury switches the balance of VSMC proliferation and apoptosis through PI3K/AKT/NF-κB signaling and consequently leads to neointimal hyperplasia. 31387172

2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 Biomarker BEFREE Notoginsenoside R1 inhibits vascular smooth muscle cell proliferation, migration and neointimal hyperplasia through PI3K/Akt signaling. 29765072

2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 Biomarker BEFREE Leptin-enhanced neointimal hyperplasia is reduced by mTOR and PI3K inhibitors. 19020099

2008