DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Alzheimer's Disease ×

Gene: ACE ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

CTD_human

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

30820047

2019

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

CTD_human

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.

17192785

2007

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

CTD_human

Alzheimer disease risk and genetic variation in ACE: a meta-analysis.

14872014

2004

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

CTD_human

Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population.

10643899

1999

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

CTD_human

Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.

9916793

1999

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

GENOMICS_ENGLAND

Entrez Id:	1636
Gene Symbol:	ACE

ACE

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.900

Biomarker

GENOMICS_ENGLAND