DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Hypertensive disease ×

Gene: CACNA1C ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	775
Gene Symbol:	CACNA1C

CACNA1C

CUI:	C0020538
Disease:	Hypertensive disease

Hypertensive disease

0.330

Biomarker

CTD_human

Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension.

22949532

2012