Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8870
Gene Symbol: IER3
IER3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.310 Biomarker CTD_human Our results suggest that hypertension in IEX-1 knockout mice may arise primarily from impaired cAMP signaling induced by overproduction of mitochondrial reactive oxygen species in vascular smooth muscle cells and demonstrate a causal relationship between mitochondrial dysfunction and cAMP-dependent vasorelaxation. 20713914

2010