Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Because of its high potency to induce inflammation, the activation and secretion of IL-1β is tightly regulated by large protein complexes, named inflammasomes. 28212736

2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Mitochondrial dysfunction promotes and aggravates the inflammatory response in normal human synoviocytes. 24609059

2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human In conclusion, the present study suggests that the neutralization of IL-1β attenuates silica-induced inflammation and fibrosis by inhibiting other inflammatory and fibrogenic mediators and modulating the Th1/Th2 balance. 23640035

2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats. 21467745

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist. 21437948

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Primary rat mesangial cells (PRMCs) were treated with IL-1β to induce inflammation to resemble glomerulonephritis. 22001142

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Genetic variation in selenoprotein S influences inflammatory response. 16227999

2005
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. 11181422

2001
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021368
Disease: Inflammation
Inflammation 		0.570 Biomarker CTD_human Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain. 9952427

1999