Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Biomarker CTD_human Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy. 17487232

2006

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Therapeutic CTD_human In conclusion, low-dose simvastatin therapy significantly improves survival and cardiac function and reduces both cardiac hypertrophy and pulmonary edema via an eNOS-dependent mechanism in a murine model of CHF. 16844920

2006

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Biomarker CTD_human In conclusion, low-dose simvastatin therapy significantly improves survival and cardiac function and reduces both cardiac hypertrophy and pulmonary edema via an eNOS-dependent mechanism in a murine model of CHF. 16844920

2006

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Therapeutic CTD_human Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy. 17487232

2006

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Biomarker CTD_human Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion. 12224825

2002

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Therapeutic CTD_human Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion. 12224825

2002

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Biomarker CTD_human Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene inhibits protein synthesis of rat ventricular cardiomyocytes. 11504159

2001

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Therapeutic CTD_human Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene inhibits protein synthesis of rat ventricular cardiomyocytes. 11504159

2001