×
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
Malignant neoplasm of lung
0.800
GeneticVariation
GWASDB
We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).
24880342 2014
×
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).
24880342 2014
×
Entrez Id: 8626
Gene Symbol: TP63
TP63
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
24880342 2014
×
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
22899653 2012
×
Entrez Id: 8626
Gene Symbol: TP63
TP63
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
23143601 2012
×
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
22899653 2012
×
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
22899653 2012
×
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
22899653 2012
×
Entrez Id: 8626
Gene Symbol: TP63
TP63
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).
21725308 2011
×
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
19654303 2009
×
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
19654303 2009
×
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
19654303 2009
×
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
18978787 2008
×
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
18385676 2008
×
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Lung cancer susceptibility locus at 5p15.33.
18978790 2008
×
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
18978787 2008
×
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
18978787 2008
×
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
18385738 2008
×
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Lung cancer susceptibility locus at 5p15.33.
18978790 2008
×
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
Malignant neoplasm of lung
0.500
GeneticVariation
GWASDB
Lung cancer susceptibility locus at 5p15.33.
18978790 2008
×
Entrez Id: 2237
Gene Symbol: FEN1
FEN1
Malignant neoplasm of lung
0.490
GeneticVariation
GWASDB
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese.
21725308 2011
×
Entrez Id: 5893
Gene Symbol: RAD52
RAD52
Malignant neoplasm of lung
0.450
GeneticVariation
GWASDB
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
22899653 2012
×
Entrez Id: 123688
Gene Symbol: HYKK
HYKK
Malignant neoplasm of lung
0.190
GeneticVariation
GWASDB
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
22899653 2012
×
Entrez Id: 123688
Gene Symbol: HYKK
HYKK
Malignant neoplasm of lung
0.190
GeneticVariation
GWASDB
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
19654303 2009
×
Entrez Id: 123688
Gene Symbol: HYKK
HYKK
Malignant neoplasm of lung
0.190
GeneticVariation
GWASDB
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.
18780872 2008