Source: UNIPROT

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT Somatic SDHB mutation in an extraadrenal pheochromocytoma. 17634472

2007
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT Combining our results with those from two other large studies in which both SDHB and SDHD have been analysed, SDHB mutations were most commonly associated with phaeochromocytoma susceptibility and SDHD with the development of HNPGL (P = 0.025). 14974914

2003
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT Germ-line mutations in nonsyndromic pheochromocytoma. 12000816

2002
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.800 GeneticVariation UNIPROT These findings extend the link between mitochondrial dysfunction and tumorigenesis and suggest that germline SDHB mutations are an important cause of pheochromocytoma susceptibility. 11404820

2001